Neem

Drug-herb combination. I'll report news of a surprising study by Japanese scientists. They combined the pharmaceutical anti-herpes drug, acyclovir (Zovirax), with any one of four tannin-rich herbal extracts: Japanese avens (Geum japonicum), Javanese sumac (Rhus javanica), cloves (Syzygium aromaticum) and chebula (Terminalia chebula). The combination treatment worked significantly better than acyclovir alone or the herbs alone. Because acyclovir is a prescription drug, you'll have to ask your doctor about trying this one.

tannins

We have formulated a Polyherbal foaming Tablet/pessary and gel (cream). The active principles are purified extracts of Neem (Azadirachta indica) leaves, saponins from Sappindus mukerosi and Mentha citrata oil. Each one of the ingredients has spermicidal and anti microbial action. Their combination has synergistic action. Quality control and quality assurance criteria have been worked out to assure reproducibility of batches.

Latin Name :	Sapindus mukorossi
English Name :	Soapnut-tree of North India
Sanskrit / Indian Names :	Phenila, Arishta

A deciduous tree found wild in north India, usually with 5-10 pairs of leaves, solitary with large drupes.

The fruit is valued for the saponins (10.1 %) present in the pericarp which constitutes up to 56.5 per cent of the drupe. The fruits are credited with expectorant and emetic properties and are used in the treatment of excessive salivation, epilepsy and chlorosis. The powdered seeds are said to possess insecticide properties. They are employed in the treatment of dental caries. It cleanses the skin of oily secretion and is even used as a cleanser for washing hair and a hair tonic, and forms a rich, natural lather. Its detergent action, which cleanses the hair and removes, accumulated debris and a sebaceous material further more imparting speculiar reflection and hair luster.

Used in Cleansing Lotion, Protein Shampoo, Protein Shampoo with Conditioner.

Click here to view detailed Herbal Monograph

Garg S Taluja V Upadhyay SN Talwar GP Studies on the contraceptive efficacy of Praneem polyherbal cream. In: Contraception (1993 Dec) 48(6):591-6 ISSN: 0010-7824 Praneem polyherbal cream, a spermicidal formulation, has been developed at the National Institute of Immunology, which makes use of Praneem, a purified extract from the dried seeds of an ancient Indian plant Azadirachta indica (Neem), extract from the pericarp of fruits of Sapindus species and quinine hydrochloride. These ingredients have a synergistic spermicidal activity and an optimised formula was derived. The components were made into a water-soluble cream base prepared by using pharmaceutically acceptable base and stabilised by addition of IP grade antioxidant and preservatives. The cream is devoid of irritation and sensitization potential, as seen with standard Draize test on normal and abraded skin of rabbits and by 21- day cumulative skin sensitivity in human volunteers. The formulation was found to be safe under subacute toxicity studies in monkeys. The formulation has shown high contraceptive efficacy in rabbits and in monkeys after intravaginal application. The shelf-life of the cream at room temperature is estimated to be 18 months by accelerated stability studies. Registry Numbers: 130-95-0 (Quinine)

http://maxpages.com/neemtree/NEEM_PRODUCTS

Research from India, China, and other countries has increased knowledge about the spermicidal characteristics of plant-based compounds such as Neem (Azadirachta indica). Researchers from South to South Cooperation in Reproductive Health are evaluating "Praneem polyherbal" cream and suppositories composed of three active ingredients: Neem seed extract (Praneem); soapnut extract (Sapindus mukerossi); and quinine hydrochloride (for anti-HIV action). Praneem polyherbal cream has exhibited high spermicidal efficacy in animal studies and is being evaluated as a treatment for vaginal infections.⁴Other plant extracts being investigated as possible spermicides with antimicrobial/antiviral properties include papain from papaya and gossypol (see Methods for Men , below ).

Praneem

Contraceptive.
Suppository, tablet and cream formulations contain citrata oil and purified extracts from neem tree.

Expanded safety trial under way in India among 300 women with abnormal vaginal discharge due to STDs; using seven-day treatment with one tablet per day.

Tests in Germany show that neem extracts are toxic to the herpes virus. Neem has anti-viral compounds that may prevent transmission and infection if a neem-based cream is used as a lubricant for intercourse.

If already contracted, neem oil has reduced the severity of genital herpes attacks when applied to the afflicted area. Genital herpes sufferers who have used neem on the sores report a tremendous reduction in the number and severity of eruptions.

Drinking two cups of neem leaf tea or taking neem capsules will enhance the immune system in its response to the virus.

$ 29.95 (US)
Become one of our thousands of satisfied customers today!

What causes Genital Herpes?

Genital herpes simplex is caused by a virus known as Herpes Simplex Virus-2.
The STD affects millions of people.
It causes painful blisters and sores in and around the genital area.

How do you get it?

It is easily spread.
Genital herpes is generally spread from an infected person to another by having sex which also includes oral and anal sex.
It can be spread even if blisters and sores can not be seen on the other person.

What are the symptoms??

painful, fluid filled blisters or sores which will burst in 10-21 days to give small, painful ulcers
Lymph nodes in the groin area can get enlarged
painful urination, especially in women
burning, tingling or itching in the genital area
discharge from genitals of males and females
fever and body aches
Sometimes, you can get cold sores around the mouth

*** For some people, there may be no symptoms ***

Where can I get help?

a doctor
a clinic
a hospital
school nurse
parents, relatives, friends
look in the yellow pages for support groups or hotlines near you
- or call:
  - Herpes Resource Center 1-800-227-8922
  - National Herpes Hotline 1-919-361-8488
Visit the SkinChoice discussion forum on herpes for information or to post a question
Purchase Herpasil which has an ingredient shown to stop intracellular infections by up to 100% (can help stop the blisters from appearing and /or shorten the outbreak)

How can I prevent it?

The best prevention is abstinence- don't have sex with multiple and unknown partners!
However if you are sexually active, always use a condom. A condom is not a 100% guarantee, but does greatly reduce the risks of contagion.
If you think that you might have herpes, stop having sex until you have been tested.
If you do have herpes, you should not have sex when blisters and sores are present.
Be honest with your partner about your condition and concerns.

Oral Herpes (Simplex I) - in and around mouth and lips
Genital Herpes (Simplex II) -on or around genitalia

" Reduced the 20 h yield of intracellular infection by up to 100%"

July, 1999 - Researchers and Scientists form Dalhousie University in Halifax, Canada publish a study with startling results: A substance isolated from the plant Prunella Vulgaris is active against Herpes Simplex 1 and 2. This substance, in laboratory studies, was MORE effective than the commonly prescribed drug Heparin, and reduced the 20 h yield of intracellular infection by up to 100%. Click here to review the article.

Soothing begins immediuately upon application

All Natural Ingredients include:

Lemon Balm	Slippery elm bark
Comfrey	St. John's Wort
Plantain Leaf	Prunella Vulgaris Extract
Calendula	Essential oils of Tea Tree, Hyssop Flower, and grapefruit.
Echinacea	Black Walnut hulls
These ingredients are then "suspended" in a base of Bees wax, and almond oil.

The isolated substance from the main active ingredient in this balm has been shown to battle Herpes Simplex 1 and 2, the viruses that cause cold sores and Genital Herpes! We spent nearly two years developing this product in conjunction with Dermatologists, Pharmacists and Universities. It is made in a special laboratory, exclusively for SkinChoice.

Suspended in a soothing balm also containing Melissa Officianalis, long prized by herpes sufferers for its effectiveness, this combination of compounds provides IMMEDIATE relief. If applied to the affected area at the first signs of an outbreak, it may help significantly reduce the duration of suffering (normally 1-3 weeks) and if applied at the first sign, may help stave off the outbreak completely!

We are the first and only company to offer an ointment like this, without prescription, containing the isolated compounds from Prunella Vulgaris. You won't find this product, or anything nearly as good, anywhere else on the planet! Safe, effective and completely confidential, why would you consider any thing else? Make the right choice - SkinChoice.

San Diego -- In the first of two reports describing novel approaches to the sexually- transmitted disease herpes, a new animal study suggests that a cream applied before sexual intercourse may prevent infection with the disease.

If the cream proves effective in humans, it will offer women another way to protect themselves from the sexually transmitted disease.

In the study, researchers found that when a chemical compound called CTC-96 was applied vaginally to mice, none of the mice became infected after being exposed to herpes simplex-2 virus (HSV-2). And even when the strength of the cream was drastically reduced, only half of the mice contracted the virus, as reported at the ICAAC conference.

The researchers also have data showing that the cream can prevent herpes infection after exposure to the virus, although the evidence for this is still preliminary.

Another study found that a traditional Chinese remedy may help treat the symptoms of the disease. An extract of the plant Prunella vulgaris can relieve the symptoms of both HSV-1 and HSV-2.

Traditionally used in China to soothe sores, the substance helps speed up the healing of sores on both the genitals and around the mouth. The researchers believe that the compound works in two ways: by stopping the virus from growing within cells and by preventing it from binding to cells. The treatment holds promise, the investigators said, especially in cases when a person has become resistant to other available treatments.

erpeStat™ Medicated Cream is the result of over four years of medical research - a laboratory tested non-prescription, self-treatment for oral and genital herpes. HerpeStat™ is a safe and effective medication for herpes sores. It consists of an emollient cream formulation containing 1% Prunella vulgaris extract that is standardized for the PVP-E active compound. 15 gm (1/2 oz.) ointment tube.

Other interesting ingredients:

http://www.forces-of-nature.net/herpes/treatment.htm terpene extracts?

Herpes simplex 1 screening of 472 plants found 10 effective: Aristolochia debilis, Artemisia anomala, Lindera strychnifolia, Patrinia villosa, Pinus massoniana, Prunella vulgaris, Pyrrosia lingua, Rhus chinensis, Sargussum fusiforme & Taraxacum mongolicum Zheng 1990

HERPESVIRUS

Prunella vulgaris has powers in vitro
SAN DIEGO-An herb could humble herpes.
So say researchers at Dalhousie University in Halifax who’ve isolated a compound in the Chinese herbal plant Prunella vulgaris that inhibits both HSV-1 and -2 in vitro.
Drs. Spencer Lee and Song Lee, noting that boiled extract from the plant is a time-honored agent against the skin lesions in Asia, say an anionic carbohydrate in the herb stops both viral growth and production of visible lesions when added to infected cells during early and late stages of infection.
They suspect it works in part by competing for cell receptors and by unknown mechanisms after the virus penetrates the cell. It was effective against viral strains known to be resistant to acyclovir (Zovirax, Glaxo Wellcome), and wasn’t toxic to mammalian cells up to the highest concentration tested, Dr. Spencer Lee told the Interscience Conference on Antimicrobial Agents and Chemotherapy here.

This Traditional Chinese topical herpes cream or ointment kills HSV I and II on contact which can reduce the risk of infection and improves healing. In addition, it also stops the herpes simplex virus from replication which also improves healing rate.

INTRODUCING: The First Herbal Topical Supplement for Cold Sores and Genital Herpes that promotes and maintains Healthy Lips and Skin, and also provides a protective barrier against Bacteria and Virus.

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Herpes Information:

Cold Sores or Fever Blisters are caused by a virus, the Herpes Simplex Virus I (HSV I) and less commonly HSV II which normally affects the genital region. Whereas, Genital Herpes is normally caused by HSV II and less commonly by HSV I. HSV II is considered a Sexually Transmitted Disease (STD).
This Virus hides near your nervous system of the affected area indefinitely and thus a cure for Cold Sores or Genital Herpes has yet to be discovered. During the replication phase of the hibernating virus, sensitive blisters appear and can last up to 3 weeks. These blisters typically recur at the same location of the lip, face or genital area. Therefore, claims by other lip treatment manufactures to offer a cure for this is simply a waste of your time and money.
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Herpes Treatment Options:

Oral prescription treatment is widely considered the Gold Standard in effectiveness for this STD. But not all anti-viral Oral prescription treatments have the same success rate for genital herpes. Caution should also be exercised with Herbal ORAL preparations because side-effect and drug-drug interaction studies have likely not been done to the extent of ORAL prescriptions. Also, anti-viral Topical prescriptions can typically reduce out-break duration for Cold Sores or Fever Blisters, but are expensive and sold in small amounts like 2 grams.

Prescription cream medications such as acyclovir and penciclovir have shown to be effective against Cold Sores because they produce anti-viral effects against HSV I but less so with HSV II. Whereas the herbal flower in Yang Zhi Herbal™ has been shown to be equally effective as treatment for both types of Herpes, including strains known to be resistant to some prescription creams.

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The Yang Zhi Herbal Advantage:

Yang Zhi Herbal™ is effective treatment that is affordable. This Chinese herb (found only along the Yang Zhi River) has been used in Eastern Medicine as a topical agent against bacteria and fungus for centuries. Most recently, it has been shown to have anti-HSV I & II activity superior to some prescription creams.

In 1999, results showed resolution of active cold sores in 3 days for individuals with recurrent episodes (8 to 10 outbreaks per year). Results in 2001 showed resolution of exposed genital herpes in less than 5 days. Most recently, an improved rate of active cold sores or genital herpes resolution have been shown with the combination of Yang Zhi Herbal™ and ibuprofen. Ibuprofen is an over-the-counter non-steroid anti-inflammatory medication that in most cases will reduce the inflammation and swelling of active herpes blisters or sores.

Also, recurrent acne around the lips, nose, and chin area that do not respond to conventional acne treatment may be the herpes simple virus (HSV). This type of facial acne typically does not improve for weeks and may not completely resolve. Yang Zhi Herbal™ can rapidly improve these HSV infected areas. Use as directed to STOP the recurrence of Herpes.

Our specially formulated Chinese Herbal Emollient has two mechanisms of action. It stops the Cold Sore and Genital Herpes Virus from replicating which stops the unsightly Sores from forming. Also it kills the herpes virus on contact which helps to limit your risk of getting a herpes infection. This cream/ointment gives high penetration, transparent, and odorless protection against the virus. Resolves active Cold Sore blisters in 2-3 days. Just like prescription formulas. Yang Zhi Herbal™ has anti-viral effects against HSV I and HSV II but at a fraction the cost. Safe to use after sexual contact.

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Comment Section:

To date we have allowed our little known products to speak on their own. Below is an example of how we value our repeat customers and their satisfaction received.

"I want to thank you for the free bottle of each of the items that I ordered. I tried the fever blister ointment a while ago, when I had a fever blister occur and your product definitely works much faster then any of the products that I bought in the drug store."
Vince De Gregory of Los Angeles, CA.
"I have had genital herpes for over 20 years. I have tried Prescription creams and pills and had very little noticable affect on the frequency and length of my outbreaks. When I tried the Yang Zhi Ointment, the duration of my infection was cut almost in half and frequency of infections is much less, now about 4 times a year. The size of the infection is also smaller. I can honestly say this product does exactly what they say it will do. I have been using it for two years now and highly recommend it over the prescription alternatives Your product works great. It heals my genital herpes infection faster and with less frequent reoccurance."
Charlie, California

"This is effective treatment. Yang Zhi Herbal™ herpes topical cream or ointment heals active herpes blisters rapidly and with regular use can stop recurrence of either herpes simplex I or II. A legitimate and excellent alternative to high priced prescription drugs, without the systemic side effects. If you get an unsightly cold sore or fever blister once or twice a year, then be prepared to never get one again."
Haselman, PhD., MD.

Repeat orders please contact us to insure your FREE PRODUCT.

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Results:

Yang Zhi Herbal™ is effective treatment that is affordable. In 1999, results showed resolution of active cold sores in 3 days for individuals with recurrent episodes (8 to 10 outbreaks per year). Results in 2001 showed resolution of exposed genital herpes in less than 5 days. Use as directed to STOP the recurrence of Herpes.

Order today. 90 day money back guarantee.

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Pricing:

$16.95 plus shipping and handling. You may also send US money order to the address at top of page. Now available 2 day delivery. Click on the "Order Now" box to see order choices. Paysystems is our merchant.

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The United States Food and Drug Administration has not evaluated this product and consequently is not intended to diagnose, treat, cure, or prevent any disease.

During the early part of this century, Neem tree was introduced in West Africa where it is valuable as a source of shade and for its medicinal properties. It has become an important source of firewood for the densely populated Accra Plains, and in countries like Somalia and Mauritania it has helped arrest the spread of the Sahara Desert. It is also grown in Saudi Arabia and in the Caribbeans and has been extensively used in afforestation programmes. Besides being able to grow in difficult conditions, Neem has the ability to control farm and household insects.

Researchers in the US Department of Agriculture have been studying this property of Neem since 1972. In laboratory experiments, it has been found that the various parts of this Neem tree has remarkable powers for controlling insects, that entomologists believe that it is now possible to develop safe natural "pesticides".

Neem leaves contain an ingredient that disrupts the fungi that produce aflatoxin on mouldy peanuts, corn, and other foods — it leaves the fungi alive, but switches off their ability to produce aflatoxin, the most powerful carcinogen known.

Neem products benefit human health.

The seeds and leaves contain compounds with demonstrated antiseptic, antiviral, and antifungal activity. There is also evidence that Neem has anti-inflammatory, hypotensive, and anti-ulcer effects.

Research has shown that compounds of Neem bark are strongly antiseptic. Neem is also effective in taking care of dental hygiene. In Germany, tests have proved that Neem extracts prevent tooth decay, as well as prevent inflammations of the gums.

The crude extract of the oil from Neem seeds can be used for various purposes like heating, lighting, or crude lubricating jobs. Refined, it loses its unpleasant smell and is used in soaps, cosmetics, toothpaste, disinfectants, and various other industrial products without having any harmful side effects.

In conclusion, Neem tree has enormous potential to benefit entire mankind.

Extracted from the bark and leaves of a hardy umbrella-shaped tree, neem can kill infectious bacteria and reduce inflammation and fever.

The neem tree is known in India as "the village pharmacy." For more than 4,500 years, traditional healers have used the bark, seeds, leaves, fruit, gum and oils for dozens of internal and external medical treatments. The most common historical uses of neem were for treatment of skin diseases, inflammation and fevers. Modern research confirms many of the traditional benefits and has revealed new ones.

Neem has demonstrated antibacterial and anti-inflammatory effects as well as benefits for those suffering from diabetes and cardiovascular disorders. One of the most intensively studied effects of neem is as an insecticide. Few people of the United States are aware of this versatile tree and its fascinating story.

Neem is a member of the mahogany family and is a hardy, fast-growing evergreen tree. It has a straight trunk, long spreading branches, grows to a height of 50 feet or more and up to 30 feet wide. These stately umbrella-shaped trees have fragrant white flowers about one-half inch across and may live for more than 200 years. While native to India, neem grows in many Asian countries, throughout arid zones of Africa and has been planted in tropical areas of the Western world as well. It thrives in poor soil and has deep roots that allow it to withstand long periods of drought.

Many of the historical and modern day uses of neem and neem oil have been to treat external skin conditions. It's little surprise that when scientists began looking at neem, they found potent antimicrobial activity. Researchers reported the antibacterial effects of the oil from the neem seed against a variety of pathogens (Indian Journal of Medical Research, 1986, vol. 84), and earlier research indicated that a water extract of neem leaves is effective against viruses (Indian Journal of Medical Research, 1969, vol. 57).

Research on the dermatological effects of neem include successful treatment of ringworm and scabies, according to a study from King George's Medical College in Lucknow, India (New Delhi Evening News, Jan. 29, 1985). Another study showed that a 10 percent extract of the leaves prevented viral skin infection in rabbits and monkeys. Leaf extracts also cured acute eczema and scabies (Antiseptic, 1979, vol. 76).

Anti-Inflammatory Effects

Neem has been used for treating rheumatism and arthritis as well as other inflammatory conditions. Numerous research studies have confirmed the herb's anti-inflammatory effects including a 1981 study showing anti-inflammatory and antipyretic (fever-reducing) properties of neem when administered orally. In the same year, Indian researchers reported anti-arthritic and anti-inflammatory actions of one of the components of neem called nimbidin (Planta Medica, 1981, vol. 43).

Neem's anti-inflammatory actions show different types of activity against acute and chronic inflammation. Neem's strong inhibition of immediate or acute inflammation suggests it prevents the release of inflammation-inducing neurochemicals including prostaglandins. In fact, one 1977 study showed neem extract to be more effective than aspirin in inhibiting prostaglandins (Journal of the West African Science Association, 1977, vol. 22).

This same aspirin-like result may be involved in the fever-reducing effect of neem, documented by some of the same studies, which showed an extract of leaf and bark administered orally could reduce fevers (Journal of Ethnopharmacology, 1985, vol. 14).

One of the more common fevers in India and throughout the tropics is malaria. Research shows neem is toxic to malaria parasites and that it can reduce fevers in malaria sufferers. Both water- and alcohol-based neem leaf extracts were confirmed effective against the parasite P. falciparum (Southeast Asian Journal of Tropical Medicine and Public Health, 1985, vol. 16). Though neem might be effective against malaria parasites, it hasn't been shown to prevent malaria infection in the body. Neem has also demonstrated some cardiovascular benefits. Studies showed a "profound and dose dependent" effect in reducing blood pressure and also in reducing arrhythmia, or irregular heartbeats (Journal of Pharmaceutical Sciences, 1978, vol. 67). The versatile herb may also favorably affect the health of diabetics. In a limited 1973 clinical trial, neem enabled diabetic patients to reduce their dosage of insulin by up to 30 to 50 percent without significant rise in blood sugar (Medicine and Surgery, 1973, vol. 13). Further research showed that oral use of leaf extracts reduced blood sugar in rabbits, rats and guinea pigs (Journal of Pharmacy and Pharmacology, 1974, vol. 26, suppl. 111).

Neem's Insecticidal Use

Neem oil is effective against insects in many ways. It's apparently so distasteful that most insects won't eat a plant treated with it, but if they do, a deadly effect occurs. Neem, harmless to humans, disrupts insect hormones, preventing the bugs from shedding their outgrown skins. The insects are thus prevented from growing and eventually die. Neem is effective against at least 200 insects and requires no sophisticated extraction or preparation equipment. Use of neem itself is bound to increase as both its medicinal and insecticidal benefits become more widely known.

The Village Pharmacy

From almost the very beginning of recorded human history, people have taken advantage of the remarkable neem tree. Even before ancient herbalists discovered the analgesic qualities of the willow tree -- from which aspirin is derived -- people used branches, fruit and leaves from the neem to cure many illnesses. Its medicinal qualities are outlined in the earliest Sanskrit writings and its uses in Hindu medicine date back to very remote times. Even today, rural Indians refer to the neem tree as their "village pharmacy" because it cures diseases and disorders ranging from bad teeth and bedbugs to ulcers and malaria.

Modern scientists are finding even more uses for this remarkable tree. The seeds, bark and leaves contain compounds with proven antiseptic, antiviral, antipyretic, anti-inflammatory, anti- ulcer and antifungal uses. Although major studies to conclusively prove neem's effectiveness are limited by financing and the general lack of knowledge in the West about it, preliminary studies suggest exciting uses for neem:

Psoriasis	Neem seed oil and leaf extracts may be the wonder cure for psoriasis. It relieves the itching and pain while reducing the scale and redness of the patchy lesions.
Diabetes	Oral doses of neem leaf extracts reduced insulin requirements by between 30% and 50% for nonkeytonic, insulin fast and insulin-sensitive diabetes
AIDS	The National Institutes of Health reports neem extracts killed the AIDS virus and patents have been awarded for these extracts as an AIDS treatment.
Cancer	Polysaccharides and limonoids found in neem bark, leaves and seed oil reduced tumors and cancers without side effects.
Heart disease	Neem delays the coagulation of blood, calms erratic heartbeats and helps reduce elevated heart rates and high blood pressure.
Periodontal disease	German researchers have proven neem extracts prevent tooth decay and periodontal disease.
Ulcers	Neem extracts give significant protection from discomfort and speed the healing of gastric and duodenal lesions.
Birth control (women)	Used as a vaginal lubricant, neem oil was up to 100 percent effective in preventing pregnancy.
Birth control (men)	In India and the United States, trials show neem extracts reduced fertility in male monkeys without inhibiting libido or sperm production, making it potentially the first male birth control pill.
Malaria	An active ingredient in neem leaves, called irodin A, is toxic to resistant strains of malaria. In vitro studies show 100 percent mortality in 72 hours with a 1:20,000 ratio.
Insect repellent	Studies have shown that one neem compound is a more effective insect repellent than the widely used synthetic chemical known as DEET (N,N,-diethyl-m- toluamide), a suspected carcinogen with long periods of use.
Insecticide	Neem extracts have been approved by the U.S. Environmental Protection Agency for use on food crops. It is non-toxic to birds, animals, beneficial insects or man and protects crops from over 200 of the most costly pests.

A key advantage to using neem, as opposed to some medical treatments and other herbs, is its compliance with the first tenant of the Hippocratic Oath taken by all physicians: "First, cause no harm." Over thousands of years, neem has been used by hundreds of millions of people and no hazards have been documented for normal dosages. Only at very high levels may neem be toxic, something each of us understands can be true of anything taken internally.

Bahama Neem Abaco Bahamas
Association	Book Marks	History
Repellents	Health	Bahamas
Agriculture	HotLinks	....

In September of 1993, Bahama Neem, Ltd. was formed with a goal of establishing the largest wholly-owned plantation of Neem trees (Azadirachta indica) in the Western Hemisphere. The project was divided into two phases:

Phase I: The initial phase of the project required securing a grant of land from the Commonwealth of the Bahamas. A total of 172 acres was granted with an additional 3,000 acres available in phases should the first acreage be fully planted. Next, Neem trees and seeds were secured, a nursery built and necessary equipment acquired. All 172 acres was cleared of extraneous plants while 66 acres was tilled and planted with 4,000 one-year old Neem trees. This phase was funded from internal sources and from secured loans.

Phase II: The second phase of the project is already under way . This phase includes tilling the remaining 106 acres, planting 6,300 additional Neem trees, maintained the grove until sustainable harvests are achieved, building a drying and processing plant and acquiring all equipment necessary for the described activities.

You can see by the picture on the left that the trees grow well in this location.

The Neem Association

The Neem Association is a non-profit organization that promotes neem as a source of natural healing and as a solution to many of the world's environmental problems. The Neem Association provides information about neem to all interested parties, material to researchers and seeds to groups supporting indigenous farmers. It supports a natural healinc clinic in Kenya and Maya farmers in Mexico.

Members receive quarterly newsletters, discounts on neem-based products and on publications by the Neem Association. New members receive a copy of the book "Neem - The Ultimate Herb" (a $12.95 value) and free samples of neem products from growers and manufacturers. Membership for the general public is $25.00 per year while non-profit groups need pay only $10.00 per year.

Please support the efforts of the Neem Association.
John Conrick, Director

Let me know what you think about my page. Send mail by clicking here.

The Neem Tree

THE HISTORY OF NEEM

NEEM AND AIDS

Neem and Birth Control

Neem and Heart Disease:

High blood pressure, blood clots, high cholesterol levels and arrhythmic heart action are major causes of heart attack. Neem leaf extracts have been shown to reduce clotting, lower blood pressure and cholesterol, slow rapid heartbeat, and inhibit irregularities of the rhythms of the heart. There are also reports that some compounds can produce effects similar to mild sedatives reducing anxiety and other emotional and physical states that can precipitate heart attacks. This may be a calming effect similar to that witnessed with other herbal teas or a psychological result of physiological effects of blood vessel dilation and lower blood pressure.

Neem and high blood pressure:

The antihistamine properties of nimbidin in leaf extracts cause blood vessels to dilate and may be responsible for reducing blood pressure. Alcoholic extract of neem leaf (intravenous ) produced a significant and immediate decrease in blood pressure which lasted for several hours. Another neem leaf extract, sodium nimbidinate, administered to people with congestive cardiac failure acted successfully as a diuretic.

Cholesterol:

Neem leaf extracts reduced cholesterol levels significantly in recent studies. Alcoholic extract of neem leaves reduced serum cholesterol by about 30% beginning two hours after administration and kept the level low for an additional four hours until the test ended.

Arrhythmia/rapid heartbeat:

Neem leaf extract exhibited anti-arrhythmic activity, returning to normal within eight minutes of administration, artificially induced arrhythmia. Neem extracts can also decrease abnormally high heart rates.

Neem and Psoriasis:

Neem oil is probably the best product currently available for treating psoriasis. It moisturizes and protects the skin while it helps heal the lesions, scaling and irritation. Experiments and reports from patients with psoriasis have shown taking neem leaf orally combined with topical treatment with neem extracts and neem seed oil appear to be at least as effective as coal tar and cortisone in treating psoriasis.

In a case study a patient with severe psoriasis was given neem extract (nimbidin) three times a day and the skin treated with nimbidin mixed in coconut oil. The treatments lasted less than three months, stopped the itching, redness and continued to improve the condition of the skin for the duration of treatment. The final result of the treatments was the complete disappearance of the signs of psoriasis. They produced no noticeable side effects. Anecdotal reports indicate that improvements are faster when the areas treated with neem are also exposed to sunlight.

The usual treatment for psoriasis involves either coal tar or cortisone. Coal tar products are messy and smell, and cortisone can thin the skin after repeated use. Neem has neither drawback. Topical applications of neem are easy and inexpensive, and since it is usually oil or cream based, neem helps to lubricate the skin. There are no unpleasant smells or stains on clothing, and its antibacterial and anti-viral compounds help prevent infections. It also can be used for extended periods of time without side effects. Neem can also take the place of oral medications and injections that may have strong side effects or cause liver damage or birth defects. It is perhaps the best and safest alternative for treating psoriasis.

Neem and Eczema:

The broad range of beneficial effects neem has on skin makes it one of the better treatments for eczema (dermatitis). Though neem oil is preferred because of the concentration of active compounds, topical applications of even the weaker leaf extracts have cured acute eczema.

Dentistry

Neem and Arthritis:

Arthritis is broad term covering many types of joint ailments. The ailments can be autoimmune disorders, infections, the result of wear on the joints or simply inflammation. Generally though it is the inflammation or the pain associated with it that is treated regardless of the origin. Neem can aid in treating arthritis in many ways. Neem's antibacterial properties can help kill infectious causes while its inflammation reducing properties and pain suppressing properties can alleviate the symptoms. Neem can also help create a balance in the immune system which directly affects progression of the disease.

A number of studies indicate the usefulness of neem in treating arthritis. There have been numerous studies on the ability of extracts of neem leaf to reduce the inflammation caused by arthritis. One study suggested that the phenolic compounds containing catechin (known to possess anti-inflammatory properties) may produce the anti- inflammatory effects witnessed. Another study discovered quercetin, a known antibacterial compound, in neem leaves. Others concluded that the polysaccharides in neem reduce the inflammation and swelling associated with arthritis.

Different parts of the tree and many extracts of each were tested . Compounds, like nimbidin, extracted from the seed with alcohol, showed significant effects against arthritis as have methanol extracts of the leaf and bark. The reason these compounds work is believed to be due to several factors. Several leaf compounds have been shown to be more potent inhibitors of prostaglandin than aspirin. Limonoids and catechin in the leaf and seed may provide additional beneficial effects. Other possible explanations point to an inhibition of the release of mediators of acute inflammation. An antihistaminic effect of nimbidin (underlying its anti-gastric ulcer activity) has been reported. Also, a modification of the immune response appears to reduce the generation of inflammation-producing chemicals.

In any case, the long history of using neem leaf, bark and seed extracts to relieve inflamed joints is borne out by the recent scientific investigations.

Neem and Rheumatism:

The active constituents in neem leaves have outstanding anti-inflammatory activity, comparable even to the well-known modern drugs phenyl butazone and cortisone. They relieve pain by acting on the prostaglandin mechanism and significantly reduce acute paw edema.

Neem and Diabetes:

Diabetes is an incurable, chronic metabolic disorder that develops when the pancreas can no longer produce sufficient insulin. Blood sugar levels rapidly elevate yet the body is unable to use the energy contained in the sugar leading to weakness and eventually unconsciousness. Diabetes is the leading cause of blindness in people ages 25 to 74, damages nerves, kidneys, the heart and blood vessels and may result in the amputation of limbs.

Neem leaf is a traditional herb for treating diabetes and has been scientifically proven effective in treating and preventing diabetes. Oral doses of neem leaf extracts significantly reduced insulin requirements for non-insulin dependent diabetes. Neem oil has also proven effective and has been able to inhibit increases in blood sugar levels by as much as 45% in test animals.

Capsules containing neem and a number of other herbs are currently available in many countries for the treatment of diabetes. In tests to verify the effectiveness of the medication (Karnim) it was found blood sugar was lowered by over 50% in twenty weeks and maintained thereafter.

Neem leaf extracts have been shown to reduce insulin requirements of diabetics without apparent effect on blood glucose levels. Different studies show insulin requirement reductions of between 20 percent and 50 percent for those who take five grams of dried neem leaf capsules. There are even anecdotal reports of diabetics chewing a single neem leaf daily that have been able to eliminate insulin injections completely.

Based on the many studies of neem's effects on insulin requirements, the Indian government has approved the sale by pharmaceutical companies of neem tablets for diabetics. (Some of these preparations are really nothing more than powdered neem leaves.)

Neem and Cancer:

The neem tree has been used successfully for centuries to reduce tumors by herbalists throughout Southeast Asia. Researchers in India, Europe and Japan have now found that polysaccharides and limonoids found in neem bark, leaves and seed oil reduced tumors and cancers and showed effectiveness against lymphocytic leukemia. In several patents issued in Japan hot water neem bark extracts showed remarkable effectiveness against several types of tumors. Several types of extract were tested at different doses and compared to the effectiveness of a standard anti-cancer agent. Several of the extracts were equal to or better than the standard anti- cancer agent against solid tumors. When the tests were done using a more purified extract of neem bark, the results were even more impressive against solid tumors. But the extracts tested were still very crude when compared to the extremely purified active compounds typically used in treating tumors. Further studies using truly pure active compounds are expected to produce results at least equal to the control.

Another researcher used an extract of neem leaves to prevent the adhesion of cancer cells to other cells in the body. Without the ability to stick to other cells, cancers cannot spread through the body and are more easily destroyed by the body's own immune system or by other treatments.

In general, neem is known for its ability to affect cancers. Injections of neem extract around tumors showed remarkable reduction in size in just a few weeks. Skin cancers may be particularly responsive to neem. A number of reports have been made by patients that skin cancers have disappeared after several months of daily application of a neem based cream.

Neem and Digestive Disorders:

Neem is regularly taken to correct problems with the stomach and bowels. Neem promotes a healthy digestive system by protecting the stomach, aiding in elimination and removing toxins and harmful bacteria.

Neem and heartburn/indigestion:

Neem leaves are often used to treat heartburn and indigestion. They are effective because some neem extracts reduce the concentration of hydrochloric acid in the stomach. Other compounds with apparent prostaglandin inhibition capabilities may also play a part in reducing gastric secretions. At the onset of indigestion traditional Ayurvedic practice is to drink a strong neem tea made with five neem leaves along with 1/4 teaspoon each of ginger and baking soda. The mixture is said to protect the stomach and reduce the discomfort.

Neem and peptic/duodenal ulcers:

Neem is a generally accepted in the Ayurvedic medical tradition as a therapy for ulcers and gastric discomfort. People throughout the Indian subcontinent take neem leaves for relief of stomach problems of any sort. Scientific validation of these practices is consistent in studies of the effectiveness of neem and neem extracts for gastric relief.

Compounds in neem have been proven to have anti-ulcerative effects. Oral doses of neem leaf extracts gave significant protection against peptic ulcers, duodenal ulcers and enhanced the healing process of gastric lesions. Nimbidin from seed extracts taken orally prevented duodenal lesions and peptic ulcers. They provided significant reductions in acid output and peptic activity of gastric fluids. The effects were most pronounced when doses were low (20 to 40 mg/kg) and increased dosages actually reduced the effectiveness of neem's anti-ulcerative effects. Neem seed extracts also showed significant healing effects from this compound for existing lesions. Similar compounds have been found in leaf extracts in lesser concentrations.

Neem and gastritis:

Neem extracts reduce the concentration of acid in the stomach and have anti-bacterial and anti-inflammatory properties that can provide relief from the effects of gastritis.

Neem and Nervous Disorders:

One hour after taking aqueous leaf extracts -- or neem tea -- weak excitation and increased activity are seen, while decreased activity and lower muscular tone occur after five hours. Nimbidin has a mild suppressive effect on the central nervous system. Neem leaf extracts produce lower activity, respiratory rate and muscle tone passivity as well as dose-dependent hypothermia. The active compounds may be limonoids, because most seem to be able to pass the blood-brain barrier.

Neem and Stress:

One of the most recent discoveries for neem revealed that extracts of neem leaves have been able to reduce anxiety and stress when ingested in small quantities. In an experiment to see what, if any, effect neem leaf extract had on anxiety and stress fresh neem leaves were crushed and the liquid squeezed out to obtain a leaf extract. The extract was then given orally to test animals who were placed in two different standard stress tests and the behavior noted. As controls and for comparison three main sets of animals were used. One group received salt water to act as a base control, another group received diazepam (Valium) and another set received the neem leaf extract. To determine the if neem leaf extract worked differently at different amounts the neem extract group was subdivided into sets that received ever larger doses.

In the elevated plus maze test doses of neem leaf extract up to 200 mg/kg showed significant anti-anxiety activity equal to or greater than diazepam. In the open field test doses of neem leaf extract up to 100 mg/kg were equal to diazepam in its anti-anxiety effect. At levels higher than 200 mg/kg and 100 mg/kg respectively the neem extract performed less well as the dosages increased until at 800 mg/kg the effect totally disappeared. The explanation for neem's anti-anxiety effect may rest with its ability to increase the amount of serotonin in the brain.

The amazing part of the experiment isn't that neem can reduce anxiety. That is something that had been reported many times before scientific experimentation finally quantified it. The amazing part is that neem extracts will only work in small doses. This unique quality of neem could make neem extract a safer alternative than drugs currently used for stress that compound their effects with higher doses up to a point where they can become dangerous.

Neem and Malaria:

Malaria affects hundreds of millions of people worldwide and kills over two million people every year. It has even made an occasional appearance in North America due to introduction of new mosquito strains and travelers from malarial regions. Malaria is transmitted from an infected person to a non-infected person by the bites of certain species of mosquito. The malarial gamete is sucked up from the infected person by the mosquito and carried in its gut until the mosquito bites an uninfected person. The bite injects the gamete into the blood stream where it travels to the kidney to mature. Neem can block the development of the gamete in an infected person. This not only prevents the infected person from developing malaria but also stops the disease from spreading.

Neem leaf extract substantially increases the state of oxidation in red blood cells, preventing normal development of the malaria plasmodia. An active ingredient in neem leaves, called Irodin A, is toxic to resistant strains of malaria, with 100 percent of the plasmodia dead in 72 hours with only a 1:20,000 ratio of active ingredients. In other experiments alcoholic extracts of neem leaf performed almost as well as the more refined compounds.

Two other compounds found in neem leaves called gedunin, a limonoid, and quercetin, a flavonoid, are at least as effective as quinine and chloroquine against malaria. Another molecule, gedunin, an extract of neem bark, has also been found to be effective in treating malaria. Several studies show that neem extracts are effective even against chloroquine-resistant strains of the malaria parasite. The antimalarial effects of neem appear to be greater in the body than on a petri dish. This has led some to speculate that stimulation of the immune system is a major factor in neem's effectiveness against malaria. Neem also lowers the fever and increases the appetite thereby strengthening the body which aids in fighting the disease parasite and speeding recovery.

Like the populations in malaria stricken ares who have access to neem some westerners familiar with neem often substitute an occasional neem leaf tea to drinking quinine on trips to malaria-infested areas of Africa and India as a preventive measure. Even though neem tea may be effective against malaria, a study done by Dr. Udeinya showed that water extracts are less effective than leaf extracts obtained by a water/acetone combination.

Neem as a Natural Insect Repellent:

Neem has been used since antiquity as an insect repellent for both people and food crops.
One compound (salannin) found in neem leaves, seeds and seed oil is a safer but more effective insect repellent than the widely used chemical ingredient called DEET (N,N-diethyl-m-toluamide) currently found in most commercial repellents.

Neem extracts tested by the Malaria Institute were found to repel the mosquito that causes malaria for up to twelve hours. Neem provides protection from not only mosquitoes but also from biting flies, sand fleas and ticks. Because of neem's proven effectiveness insect repellents made with neem are being used in malaria prone tropical countries.

For those seeking a safe alternative to potentially dangerous synthetic repellents neem offers an attractive alternative for the following reasons:

Neem oil is an excellent skin moisturizer while DEET is not recommended for repeated application to the skin, around the face or on the hands of small children.

Neem oil is a natural vegetable oil while DEET is not recommended to be sprayed on furniture, plastics, watch crystals, leather and painted surfaces including automobiles. DEET may actually dissolve all synthetic fabrics but nylon.

Neem oil has been used safely for centuries while DEET is a synthetic chemical that has only been used for a short time and may pose future unknown health risks. Many researchers believe DEET to be partly responsible for the devastating effects of Gulf War Syndrome.

Neem is a healing herb that is famous for its wound healing properties. Cuts, scrapes and poison oak and ivy can be salved with neem oil lotions. DEET (a synthetic insect repellent) products contain warnings against getting them in open sores or on damaged skin.

Neem in Agriculture

As scientists scour rainforests in dangerous and inaccessible areas of the world in search of useful plants, the neem tree grows inconspicuously in the front yards of homes and on college campuses throughout south Asia and Africa. It is this familiarity that had hidden the true miracle of neem until a few scientists took a closer look at this ancient and sacred tree. Researchers worldwide are now focusing on the neem tree and the hundreds of active compounds it produces to try to determine how one tree can do so many things so well. But it is in agriculture that we find most of the research on neem being conducted today.

Neem in a Kenyan Herbal Clinic

Neem helping farmers in developing countries

Neem's "soft" pesticide is improving the lives of impoverished farmers throughout the tropical range of the neem tree. Substituting crude neem extracts for expensive chemical controls saves both money and lives. In developing countries, it is estimated 500,000 people are poisoned and up to 20,000 die annually from using agricultural chemicals. To protect their crops, most of the earnings of farmers in developing countries are spent on these chemicals, producing a cycle that leads not to more food and a better life, but to continued poverty, ill health and environmental degradation.

To break this cycle and to improve the farmer's lives, agencies such as CARE, AID and AFGRO are actively promoting the introduction and use of neem in Southeast Asia, Africa, the Caribbean and both South and Central America. Seedlings and educational programs give the farmers the means and methods for easily making a cheap, safe and effective product that protects their crops from over 200 different insect pests, including the desert locust.

Farmers in Mexico and Haiti and shepherds in Australia have begun switching to simple neem-based sprays from the usual synthetic chemical pest controls. This has allowed the farmers to export mangos and other fruit to the United States without the chemical residues that often stopped their shipments at inspection stations. Neem-based sprays have similarly allowed the shepherds in Australia to produce a pesticide-free wool that is being sold to European buyers for a considerable premium over the standard wool impregnated with chemical pesticides.

Food Storage:

Throughout the tropics much of the food harvested is lost during storage. More affluent farmers can and do spray their stored food crops with chemical pesticides to prevent worms, beetles and other infestations. Neem offers the impoverished farmers and even affluent farmers wanting to replace pesticides a natural and inexpensive alternative. A light coating of neem oil protects stored food crops for up to twenty months from all types of infestations with no deterioration or loss of palatability.

Soil Amendment - Neem Cake:

After the oil has been pressed from the seed kernels, the remaining material is called "neem cake." This material has been used for many centuries throughout India as a soil amendment. Experience has taught farmers there that working the left-over neem cake into the soil of a garden produces larger, healthier plants that have few problems with insect pests.
Several studies were done to find out why plants grew better in soils mixed with neem cake. The studies discovered that neem cake was richer in plant nutrients than manure, killed damaging nematodes, promoted larger populations of earthworms, helped keep nitrogen in the soil available for the plants, and provided significant protection from insects. This combination of effects provides an almost ideal growing condition for the plants.
By killing nematodes in the soil, a major plant pest is eliminated. Nematodes suck the juices from the roots of plants to the point where they are unable to supply sufficient nutrients to the plant. The plants look sickly, fail to grow and may eventually die despite sufficient food, water and care. On the other hand, by promoting larger populations of earthworms, neem cake helps keep the soil loose so that water and nutrients can more easily be absorbed by the roots. Earthworms also enrich the soil by creating readily absorbable nutrients as it feeds on decaying plant material. Neem cake also reduces the nitrification rate of the soil by suppressing nitrifying bacteria such as nitrosomonas and nitrobacter bacteria. This reduces the need for applications of external nutrients. Some studies have shown that mixing neem cake with regularly scheduled applications of manure can almost double crop yield over manure alone.

The Neem Association

The National Research Council produced a landmark book, "Neem - A Tree for Solving Global Problems". It may be found in your local library or ordered from National Academy Press online under National Academy of Science.

Neem Tree - India's "Village Pharmacy"

The neem tree could have been designed by a celestial committee (maybe it was). A collaboration of genetic engineers, chemical engineers, pharmacists, agronomists, and dieticians could not have produced a more interesting, and some say, valuable, plant. I'll let you decide after reading this brief overview.

Azadirachta indica is "tailor-made for combating the serious problems confronting mankind today" says the Neem Foundation. " Studies through appropriate scientific channels are increasing and verifying the traditional uses and are finding even more uses for neem. Although major studies to conclusively prove neem's effectiveness are limited by financing and the general lack of knowledge in the West about it, preliminary studies suggest exciting uses for neem."

From the very beginning of recorded human history, people have used the mysterious neem tree. Today, rural Indians call this tree their "village pharmacy" because it "cures" diseases and disorders ranging from bad teeth and bedbugs to ulcers and malaria. The seeds, bark and leaves contain compounds called limonoids with proven antiseptic, antiviral, antipyretic, anti-inflammatory, anti-ulcer and antifungal uses.

Neem has a cousin that is a very familiar tree in the United States called the Chinaberry. Many North Americans are familiar with the abundant Chinaberry tree, Melia azedarach. Also known as umbrella tree, this naturalized western Asian tree is a colonizer of disturbed sites throughout the South. It can be messy with surface roots, brittle wood, and toxic berries. However, it has an ability to grow in hostile sites and produce desirable shade.

Neem, on the other hand, is a sturdy, broadleaved evergreen. In the seasonally dry hills of central India, Azadirachta indica, is very much in existence with the people and animals in villages and along roadsides. It will defoliate during periods of extreme drought or freezing temperatures. Native to the dry forest areas of India, Pakistan and Sri Lanka, neem thrives in the dry areas of the tropics and subtropics.

Mature neem trees are capable of withstanding mild freezes and can be grown in some of the United States south, along coastal California to San Francisco and on the East coast as far north as central Florida. In freeze zones they must be grown potted and taken in during cold snaps.

I was shocked at the reported uses of the neem tree. Most of this is supported by some scientific study. Much more investigation is needed, however.

Multitude of Uses and Remedies Include:

• AIDS - The National Institutes of Health reports encouraging results as an AIDS preventative and possible cure using neem extracts.

• Allergies - Neem inhibits allergic reactions when applied externally or eaten.

• Birth control (men) - In India and the United States, trials show neem extracts reduced fertility in male monkeys without inhibiting libido or sperm production, making it potentially the first male birth control pill.

• Birth control (women) - Used as a vaginal lubricant, neem oil was up to 100 percent effective in preventing pregnancy.

• Cancer/immune - Polysaccharides and limonoids found in neem bark, leaves, and seed oil increased immune responses, reduced tumors and cancers without side effects.

• Diabetes - Oral doses of neem leaf extracts reduced insulin requirements by between 30% and 50% for nonkeytonic, insulin fast and insulin-sensitive diabetes.

• External parasites - Neem quickly kills external parasites and a neem decoction is safer and just as effective as standard treatments for head lice and scabies.

• Heart disease - Neem delays the coagulation of blood, calms erratic heartbeats and helps reduce elevated heart rates and high blood pressure.

• Herpes - Recent tests in Germany show that neem extracts are toxic to the herpes virus and can quickly heal cold sores.

• Hepatitis - Tests in the U.S. show neem hampers the virus that causes hepatitis B.

• Fungal toxin - Neem is toxic to several fungi which attack humans, including those that cause athlete's foot and ringworm, and Candida, an organism that causes yeast infections and thrush.

• Insect repellent - Studies have shown that one neem compound is a more effective insect repellent than the widely used synthetic chemical known as DEET (N,N,-diethyl-m-toluamide), a suspected carcinogen with long periods of use.

• Insecticide - Neem extracts have been approved by the U.S. Environmental Protection Agency for use on food crops. It is non-toxic to birds, animals, beneficial insects or man and protects crops from over 200 of the most costly pests.

• Malaria - An active ingredient in neem leaves, called irodin A, is toxic to resistant strains of malaria.

• Psoriasis - Neem seed oil and leaf extracts is suggested to be a cure for psoriasis. It relieves the itching and pain while reducing the scale and redness of the patchy lesions.

• Periodontal disease control - German researchers have proven neem extracts prevent tooth decay and periodontal disease.

• Soap/Shampoo - Neem oil soaps can be used to treat a variety of illnesses and ailments.

• Ulcer relief - Neem extracts give significant protection from discomfort and speed the healing of gastric problems.

More Information:

Azadirachtin
A powerful antifeedant most specifically located in the seed kernel.

alt.cancer.com - Neem
"Few plants can claim to be as useful for such a broad array of medical problems as the Neem Tree (Azadirachta indica)."

TheNeemTree.com
"A tree for solving global problems."

Rainforest Plant Seed
Buy Neem seed from Seeds Etc.

Bioagro Neem
"Murkumbi Bioagro is an agri-biotech company based in India. We manufacture and market innovative, eco-friendly agro-inputs and natural products by tapping nature’s resources."

Woman

Vaginal creams and suppositories made with neem oil are quickly becoming the birth control method of choice in India. They are non-irritating and easy to use while almost 100 percent effective. It's important to note, however, that even toxic spermicides are not 100 percent effective. When tested against human sperm neem extract (sodium nimbidinate) at 1000 mg was able to kill all sperm in just 5 minutes and required only 30 minutes at a 250 mg level. They have the added benefit of preventing vaginal and sexually transmitted diseases like gonorrhea, syphilis and chlamydia.

Neem has a proven ability to prevent pregnancy. Neem oil has also been shown to work well both before and after sex while some purified extracts only worked before sex as a preventative. Neem oil appears to be the most effective form of neem for birth control, particularly hexane extracted neem oil. After a single injection of a minute amount of neem oil in the uterine horns, a strong cell-mediated immune response reaction produced a long term (up to 12 months) and reversible block in fertility. There were no changes in menstrual cycles or ovarian function.

Neem oil has also been found to prevent implantation and may even have an abortifacient effect similar to pennyroyal, juniper berries, wild ginger, myrrh and angelica. The effects were seen as many as ten days after fertilization in rats though it was most effective at no more than three days. In a study on rats, neem oil was given orally eight to ten days after implantation of the fetus on the uterine wall. In all cases, by day 15, the embryos were all completely resorbed by the body. The animals regained fertility on the next cycle showing no physical problems. Detailed study of the rats revealed increased levels of gamma interferon in the uterus and enhanced local immune response in the uterus. Post coital use of neem oil as birth control does not appear to work by hormonal changes but produces changes in the organs that make pregnancy no longer viable.

Years of study in India by some of the world's leading scientists resulted in the development of a neem-based polyherbal vaginal cream that has both spermicidal and anti-microbial action. The cream combines 25 per cent neem seed extract with extracts from the soap nut and quinine hydrochloride. Based on the success of these experiments, a neem-based contraceptive cream was developed by a pharmaceutical company in India. Tests of its effectiveness showed that it compared favorably with the chemical-based foams and gels. It was safer and easier to use, caused no irritation or discomfort, was nearly 100% effective, and was therefore used more frequently than the foam or gel spermicides. The effect does not appear to be hormonal and is considered a safe and effective alternative to other methods that use hormones.

Men

Neem may become the first truly effective birth control "pill" for men. Neem oil capsules ingested for one month produced reversible male antifertility without affecting sperm production or libido. In India and the United States, exploratory trials show neem extracts reduced fertility in male monkeys without inhibiting libido or sperm production.

In a test of neem's birth control effects with members of the Indian Army, daily oral doses of several drops of neem seed oil in gelatin capsules were given to twenty married soldiers. The effect took six weeks to become 100 percent effective, it remained effective during the entire year of the trial and was reversed six weeks after the subjects stopped taking the capsules. During this time the men experienced no adverse side effects and retained their normal capabilities and desires. There were no pregnancies of any of the wives during the period of the study.

For long term birth control for men it appears that a very minute amount of neem oil injected in the vas deferens provides up to eight months of birth control. The tests revealed no obstructions, no change in testosterone production and no anti-sperm antibodies. The local lymph nodes showed increased ability to respond to infections indicating an immune response may be responsible for the birth control effect in men as it is in women.

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Bahama Neem

Neem has immuno-stimulating properties for both the lymphocytic and cell-mediated immune systems. When human white blood cells infected with HIV were cultured with neem extracts, the production of viral proteins dropped dramatically. Dr. Upadhyay and Dr. Berre'- Sinousi (one of the scientists who identified the AIDS virus) believe the neem extracts block production of viral proteins thereby stopping replication of the virus.

Studies of the effects of neem bark and neem leaf extracts show they significantly reduced the P-24 viral proteins and induced in vitro production of IL-1 interferon. The National Institutes of Health, in a preliminary study, reports encouraging results from in vitro tests where neem bark extracts killed the AIDS virus. Another possible effect neem may have on combating the AIDS virus is its apparent ability to enhance the cell-mediated immune response to infection. Using extracts made by soaking neem bark in water,

Dr. Van Der Nat (Netherlands) determined that the extract produces a strong immune stimulating reaction. The neem bark extract stimulated lymphocyte function which increased production of MIF, a lymphokine that attaches macrophages and monocytes to infectious agents.

Believed to be the first line of defense against HIV infection, neem's ability to enhance the cell-mediated immune response may provide protection from vaginal contraction of the disease if neem is used as a vaginal lubricant before intercourse. If even only partially successful in preventing the spread of AIDS, until scientists develop a cure, neem could save countless lives.

In cases where HIV has not advanced to full-blown AIDS some of the patients appear to have the enhanced cell-mediated immune responses that neem can help produce. However, once contracted, AIDS may be treated by ingesting neem leaf extracts, whole leaf or by drinking neem tea.

Many of the complications associated with AIDS can also be treated with neem leaf or bark and creams. Lesions of the skin or burning sensations have been successfully treated with neem leaves added to bath water and by lotions containing neem oil.

Neem and the Immune System:
Neem, especially neem bark, is recognized for its immunomodulatory polysaccharide compounds. These compounds appear to increase antibody production. Other compounds in neem enhance the immune system via a different mechanism; the cell- mediated immune response, the body's first form of defense. Only when this system appears to be unable to stop an infectious onslaught is the more massive immune system involved.

Neem oil acts as a non-specific immuno-stimulant that activates the cell mediated immune response. This then creates an enhanced response to any future challenges by disease organisms. When neem oil was injected under the skin there was a significant increase in leukocytic cells and perioneal macrophages showed enhanced phagocytic activity and expression of MHC class II antigens. Production of gamma interferon was also induced by the injection. Spleen cells showed higher lymphocyte reaction to infection but did not augment anti-TT antibody response.

Water soluble neem leaf extracts, when taken orally, produced an increase in lymphomatic counts and both red and white blood cells as well as lymphocyte counts. In studies on the birth control effects of neem the major factor in that effect appears to be an increase in the immune response where neem has been applied that causes the body to reject the fetus as a foreign body.

By enhancing the cellular immune response most pathogens can be eliminated before they cause the ill feeling associated with disease. This mechanism could also help in diseases that involve the immune system, like AIDS. Ingesting small quantities of neem leaf or bark powder every other day or drinking a mild neem tea will enhance antibody production and the body's cell-mediated immune response, helping to prevent infections.

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Bahama Neem

AROMATHERAPY : A NATURAL INSECT REPELLENT ?
That plants have a natural defence system to discourage potential enemies, is well known. A good example is the cactus which sharp needles has been a source of pain for many human beings, but also repels animals wishing to eat it.
Other plants have such a horribly taste, that no animal would even think of eating from it. Of many species the taste is so repulsive, that potential enemies prefer to stay away from it.
One of these is the Neem Tree.
This tree is something short of a miracle. It's origins are in India, where the local population refer to it as the village pharmacy. At present we can find the trees in many other countries, even in the USA (Texas).
One in every 5 houses in India has a Neem Tree as the people feel that the Tree does well for the occupants of the house. A blind believe ? Hardly, if you consider that almost every part of the tree has some use.
The Neem tree , the Azadirachta indica, a cousin of the better known Chinaberry tree the Melia azedarach, offers protection against the burning sun by means of its dense and thick green leaves. But providing protection against the burning sun is not the only reason Neem is grown.
For centuries adults have gone early morning to the tree, cut a tender branch and use it as a tooth brush. Modern science has proven that the juice of the tree successfully prevents periodontal disease.
Indians consider the powder, made from dried Neem leaves a good disinfectant and natural antibiotic which they use on secondary infections and boils. Neem decoction is also given for common fevers. A crude antiseptic soap is made from the pulp of the olive like fruit. A