Calendula

Organic flower extract for HIV
Sean Hosein
In lab experiments low concentrations of the organic extract, but not the freeze-dried extract, protected about 90% of cells from death due to HIV. The plant extract did not appear to cause any toxicity. Calendula's anti-HIV activity occurs because the plant affects a vital viral enzyme called RT (reverse transcriptase) which is also the target of AZT and the "related" drugs, 3TC, d4T, ddC, ddI and 1592.

Calendula officinalis - Marigold - soothing. Excellent for irritated and delicate skin. Has antiseptic properties.

 

Monograph : Calendula officinalis

  Calendula officinalis
Calendula officinalis
Common name: calendula

Other names: marigold, garden marigold, pot marigold, holigold, mary bud, morgenfrue, ringelblume

Family: Asteraceae

Parts used: flowers


Description
Historical Use
Dose Dry Herb
Dose Extract
Indications
Qualities
Actions
Constituents
Toxicology
Pharmacological Studies
Clinical Studies


Description
Calendula is a hardy annual or short-lived perennial, growing to 50 cm. Stems are branching, angular, covered with short erect gluandular hairs. Large yellow or orange flower heads are borne throughout much of the year, though less so in the winter.

Calendula is indigenous to Egypt and Mediterranean Europe.

Historical use
The ancient Greeks were known to use Calendula, and before them the Indian and Arabic cultures. It has been used for medicinal, culinary and cosmetic purposes; also boiled to obtain its yellow dye. The botanical name comes from the Latin calendulae or calends meaning 'throughout the months', to emphasise the very long flowering period of the plant.1

The BHP lists the specific indications of calendula as enlarged or inflamed lymphatic nodes, sebaceous cysts, duodenal ulcer, and acute or chronic inflammatory skin lesions. Other indications include amenorrhoea, dysmenorrhoea, epistaxis, proctitis, and as an eye lotion for conjunctivitis.2

The internal and topical use of calendula flower was approved by Commission E for inflammation of the oral and pharyngeal mucosa; also topically for poorly healing wounds.3 Calendula is often referred to as marigold, however the name marigold is also used for garden ornamentals of a different genus. Grieve notes that only the common deep orange-flowered variety of calendula is of medicinal value.4
_____________
1Stuart M, (ed), 1979, The Colour Dictionary of Herbs & Herbalism, Orbis Publishing, London, p 36.
2British Herbal Medicine Association, 1983, British Herbal Pharmacopoeia, West Yorks, p 45.
3Kommission E monographs, 1991, p 45.
4Grieve M, 1994 (first published in 1931), A Modern Herbal, Tiger Books International, London, p 518.

Toxicology
None known.

DoseDryHerb
3 to 12 g per day.

DoseExtract
10 to 30 mL per week (1:2). Use 90% extract for fungal infections and 25% for viral infections.

Indications
acne, acne (topically), boils (poultice), cholecystitis, dysmenorrhoea, spasmodic, eczema, eczema (topically), gastritis, glands, swollen, haemorrhoids (topically), hypercholesterolaemia, infection, inflammation, gastrointestinal tract, menopause, hypertension and arrhythmias, menstrual irregularity, pruritus, psoriasis, ulcer, gastriointestinal, ulcer, mouth, varicose veins (topically), wounds (topically)

Qualities
cooling potential, dry

Actions
anti-inflammatory, anti-inflammatory (GIT), anti-inflammatory (topically), antimicrobial, antiseptic (GIT), antiseptic (topically), antiviral (topically), astringent, cholagogue, choleretic, hypocholesterolaemic, hypolipidaemic, lymphatic, vulnerary

Constituents
Key active constituents:

  • triterpenoid saponins, including the aglycones oleanolic acid, oleanoic acid and saponosides A to F
  • 2-4% triterpenol alcohols, either in the free form or as esters
  • carotenoids, the content of which determines the colour of the flowers: carotene in orange flowers, xanthophyll in yellow flowers
  • flavonoids, especially isorhamnetin glycosides
  • essential oil, consisting of mono and sesquiterpenes
  • bitter principles including calendin
Also polyacetylenes, polysaccharides, and manganese


Pharmacological studies
Immunomodulatory effects




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